Origins of the specificity of inhibitor P218 toward wild-type and mutantPfDHFR: a molecular dynamics analysis
Author:
Publisher
Informa UK Limited
Subject
Molecular Biology,General Medicine,Structural Biology
Link
http://www.tandfonline.com/doi/pdf/10.1080/10256018808623883
Reference63 articles.
1. Design and synthesis of guanylthiourea derivatives as potential inhibitors of Plasmodium falciparum dihydrofolate reductase enzyme
2. 3D-QSAR analysis of cycloguanil derivatives as inhibitors of A16V+S108T mutant Plasmodium falciparum dihydrofolate reductase enzyme
3. Binding modes of 2,4-diaminoquinazoline and 2,4-diaminopteridine analogs to P. falciparum dihydrofolate reductase enzyme: Molecular docking studies
4. Computer-aided molecular design of 1H-imidazole-2,4-diamine derivatives as potential inhibitors of Plasmodium falciparum DHFR enzyme
5. A common feature-based 3D-pharmacophore model generation and virtual screening: identification of potential PfDHFR inhibitors
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