Action Models for the Antitumor Drug Camptothecin: Formation of Alkali-labile Complex with DNA and Inhibition of Human DNA Topoisomerase I
Author:
Publisher
Informa UK Limited
Subject
Molecular Biology,General Medicine,Structural Biology
Link
http://www.tandfonline.com/doi/pdf/10.1080/10256018808623883
Reference50 articles.
1. Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2
2. DNA Topoisomerase I—Targeted Chemotherapy of Human Colon Cancer in Xenografts
3. The clinical status of irinotecan (CPT-11), a novel water soluble camptothecin analogue: 1996
4. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.
5. On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex
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