Determination of potential selective inhibitors for ROCKI and ROCKII isoforms with molecular modeling techniques: structure based docking, ADMET and molecular dynamics simulation-Reference-Cited by-同舟云学术

Determination of potential selective inhibitors for ROCKI and ROCKII isoforms with molecular modeling techniques: structure based docking, ADMET and molecular dynamics simulation

Published:2018-10-26 Issue:9 Volume:37 Page:2457-2463
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Bayel Secinti Burcu¹,Tatar Gizem¹,Taskin Tok Tugba²^ORCID

Affiliation:

1. Department of Bioinformatics and Computational Biology, Gaziantep University, Institute of Health Sciences, Gaziantep, Turkey;

2. Faculty of Arts and Sciences, Department of Chemistry, Gaziantep University, Gaziantep, TurkeyCommunicated by Ramaswamy H. Sarma

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2018.1491420

Reference29 articles.

1. Design, Synthesis, and Biological Evaluation of Novel, Highly Active Soft ROCK Inhibitors

2. Amino acid derived quinazolines as Rock/PKA inhibitors

3. Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension

4. Dassault Systèmes BIOVIA, Discovery Studio Modeling Environment, Release 2017, San Diego: Dassault Systèmes, (2016).

5. Rho Kinase (ROCK) Inhibitors and Their Therapeutic Potential

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