A structure-based approach for the discovery of inhibitors against methylcitrate synthase of Paracoccidioides lutzii-Reference-Cited by-同舟云学术

A structure-based approach for the discovery of inhibitors against methylcitrate synthase of Paracoccidioides lutzii

Published:2021-06-01 Issue: Volume: Page:1-13
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Lima Raisa Melo¹²^ORCID,Freitas e Silva Kleber Santiago¹,Silva Lívia do Carmo²,Ribeiro Jean Francisco Rosa²,Neves Bruno Junior³,Brock Matthias⁴,Soares Célia Maria de Almeida¹,da Silva Roosevelt Alves⁵^ORCID,Pereira Maristela¹²^ORCID

Affiliation:

1. Molecular Biology Laboratory, Institute of Biological Sciences, Federal University of Goiás, Brazil

2. Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil

3. Faculty of Pharmacy, Laboratory for Molecular Modeling and Drug Design, Federal University of Goiás, Goiânia, Brazil

4. School of Life Science, Fungal Biology Group, University of Nottingham, Nottingham, UK

5. Collaborative Nucleus of Biosystems, Institute of Exact Sciences, Federal University of Jataí, Jataí, Brazil

Funder

Ministério da Ciência e Tecnologia/Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundo Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado de Goiás

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior/Finance Code 001

Financiadora de Estudos e Projetos

Programa de Apoio a Núcleos de Excelência

Instituto Nacional de Ciência e Tecnologia de Estratégias de Interação Patógeno-Hospedeiro

FAPEG NEWTON programme

MRC-Newton programme

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2021.1930584

Reference61 articles.

1. Identification of New Antifungal Compounds Targeting Thioredoxin Reductase of Paracoccidioides Genus

2. Comparative genomics allowed the identification of drug targets against human fungal pathogens

3. Methylmalonyl-CoA Epimerase Deficiency Mimicking Propionic Aciduria

4. Effects of Argentilactone on the Transcriptional Profile, Cell Wall and Oxidative Stress of Paracoccidioides spp.

5. Targeting the Homoserine Dehydrogenase of Paracoccidioides Species for Treatment of Systemic Fungal Infections

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