Prediction of pharmacokinetic clearance and potential Drug-Drug interactions for omeprazole in the horse using in vitro systems-Reference-Cited by-同舟云学术

Prediction of pharmacokinetic clearance and potential Drug-Drug interactions for omeprazole in the horse using in vitro systems

Published:2020-05-20 Issue:10 Volume:50 Page:1220-1227
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Shibany Khaled A.¹,Pratt Stefanie L.¹,Aldurdunji Mohammed¹,Totemeyer Sabine¹,Paine Stuart W.¹^ORCID

Affiliation:

1. School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Loughborough, United Kingdom of Great Britain and Northern Ireland

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2020.1764131

Reference29 articles.

1. THE BINDING OF DRUGS TO HEPATOCYTES AND ITS RELATIONSHIP TO PHYSICOCHEMICAL PROPERTIES

2. The prevalence and distribution of gastric ulceration in 345 racehorses

3. Qualitative and Quantitative Assessment of Drug-Drug Interaction Potential in Man, Based on Ki, IC50 and Inhibitor Concentration

4. Pharmacokinetic Drug Interaction Profiles of Proton Pump Inhibitors

5. An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons

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1. Identification and kinetics of microsomal and recombinant equine liver cytochrome P450 enzymes responsible for in vitro metabolism of omeprazole;Biochemical Pharmacology;2023-08

2. Utilizing virtual experiments to increase understanding of discrepancies involving in vitro-to-in vivo predictions of hepatic clearance;PLOS ONE;2022-07-22

3. Nonlinear Mixed-Effect Pharmacokinetic Modeling and Distribution of Doxycycline in Healthy Female Donkeys after Multiple Intragastric Dosing–Preliminary Investigation;Animals;2021-07-09

4. Utilizing virtual experiments to increase understanding of discrepancies involving in vitro-in vivo predictions of hepatic clearance;2020-10-10