Identification of in vivo metabolites of a potential anti-rheumatoid arthritis compound, the quinazolinone derivative PD110, using ultra-high performance liquid chromatography coupled with Q-Exactive plus mass spectrometrys-Reference-Cited by-同舟云学术

Identification of in vivo metabolites of a potential anti-rheumatoid arthritis compound, the quinazolinone derivative PD110, using ultra-high performance liquid chromatography coupled with Q-Exactive plus mass spectrometrys

Published:2022-03-04 Issue:3 Volume:52 Page:284-294
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Wang Huan¹²,Tang Minghai²,Qiu Xiang¹,Tan Yan¹²,Guo Yong²,Liu Kongjun²,Li Xiandeng¹,Wu Wenshuang³⁴,Wan Li¹

Affiliation:

1. School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China

2. State Key Laboratory of Biotherapy and Cancer Center; West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China

3. Department of Thyroid Surgery, West China Hospital, Sichuan University, Chengdu, China

4. Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2022.2062684

Reference23 articles.

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3. Class 1 PI3K Clinical Candidates and Recent Inhibitor Design Strategies: A Medicinal Chemistry Perspective

4. PI3K inhibition in inflammation: Toward tailored therapies for specific diseases

5. PI3K signalling in inflammation

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