Discovery and in Vivo Evaluation of (S)-N-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and Related PI3Kδ Inhibitors for Inflammation and Autoimmune Disease-Reference-Cited by-同舟云学术

Discovery and in Vivo Evaluation of (S)-N-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and Related PI3Kδ Inhibitors for Inflammation and Autoimmune Disease

Published:2014-12-03 Issue:1 Volume:58 Page:480-511
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cushing Timothy D.,Hao Xiaolin,Shin Youngsook,Andrews Kristin,Brown Matthew,Cardozo Mario,Chen Yi,Duquette Jason,Fisher Ben,Gonzalez-Lopez de Turiso Felix,He Xiao,Henne Kirk R.,Hu Yi-Ling,Hungate Randall,Johnson Michael G.,Kelly Ron C.,Lucas Brian,McCarter John D.,McGee Lawrence R.,Medina Julio C.,San Miguel Tisha,Mohn Deanna,Pattaropong Vatee,Pettus Liping H.,Reichelt Andreas,Rzasa Robert M.,Seganish Jennifer,Tasker Andrew S.,Wahl Robert C.,Wannberg Sharon,Whittington Douglas A.¹,Whoriskey John,Yu Gang,Zalameda Leeanne,Zhang Dawei,Metz Daniela P.

Affiliation:

1. Department of Therapeutic Discovery, Amgen Inc., 360 Binney Street, Cambridge, Massachusetts 02142, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501624r

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