Approaches to Improve the Translation of Safety, Pharmacokinetics and Therapeutic Index of ADCs-Reference-Cited by-同舟云学术

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Approaches to Improve the Translation of Safety, Pharmacokinetics and Therapeutic Index of ADCs

Published:2024-05-11 Issue: Volume: Page:1-16
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Huang Qihong¹,Ravindra Pilvankar Minu²,Dixit Rakesh³,Yu Hongbin²

Affiliation:

1. Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, Ridgefield, CT, USA 06877

2. NBE PK, Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, Ridgefield, CT, USA 06877

3. Bionavigen Oncology, LLC, GAITHERSBURG, MD, USA 20878

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2024.2352600

Reference65 articles.

1. Lysosomal-Cleavable Peptide Linkers in Antibody–Drug Conjugates

2. Strategies and challenges for the next generation of antibody–drug conjugates

3. Antibody–Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs

4. Use of translational modeling and simulation for quantitative comparison of PF-06804103, a new generation HER2 ADC, with Trastuzumab-DM1

5. Association of Animal Models in the Field of Translational Medicine: Prediction and Validation

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Preface for Special Issue: “Emerging strategies, technologies and approaches for the next generation ADCs”;Xenobiotica;2024-07-29

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