Impact of cytochrome P450 variation on meperidine N-demethylation to the neurotoxic metabolite normeperidine
Author:
Affiliation:
1. Department of Pharmaceutical Sciences, Lipscomb University College of Pharmacy and Health Sciences, Nashville, TN, USA;
2. Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, USA
Funder
American Foundation for Pharmaceutical Education Gateway to Research Scholarship
Lipscomb University College of Pharmacy Dean’s Grant
National Cancer Institute of the National Institutes of Health
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2019.1599465
Reference44 articles.
1. Expression of Hepatic Drug-Metabolizing Cytochrome P450 Enzymes and Their Intercorrelations: A Meta-Analysis
2. Fluvoxamine is a potent inhibitor of cytochrome P4501A2
3. Standardizing terms for clinical pharmacogenetic test results: consensus terms from the Clinical Pharmacogenetics Implementation Consortium (CPIC)
4. Meperidine: Therapeutic use and toxicity
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