Human total clearance values and volumes of distribution of typical human cytochrome P450 2C9/19 substrates predicted by single-species allometric scaling using pharmacokinetic data sets from common marmosets genotyped for P450 2C19-Reference-Cited by-同舟云学术

Human total clearance values and volumes of distribution of typical human cytochrome P450 2C9/19 substrates predicted by single-species allometric scaling using pharmacokinetic data sets from common marmosets genotyped for P450 2C19

Published:2021-01-17 Issue:4 Volume:51 Page:479-493
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Matsumoto Shogo¹^ORCID,Uehara Shotaro²³^ORCID,Kamimura Hidetaka²⁴^ORCID,Ikeda Hiroshi⁵,Maeda Satoshi⁶,Hattori Machiko⁶,Nishiwaki Megumi⁷,Kato Kazuhiko¹,Yamazaki Hiroshi³^ORCID

Affiliation:

1. Pharmaceutical Research Labs., Meiji Seika Pharma Co., Ltd., Yokohama, Japan

2. Central Institute for Experimental Animals, Kawasaki, Japan

3. Pharmaceutical University, Machida, Tokyo, Japan

4. Business Promotion Dept., CLEA Japan, Inc., Tokyo, Japan

5. Tokyo Animal & Diet Dept., CLEA Japan, Inc., Tokyo, Japan

6. Yaotsu Breeding Center, CLEA Japan, Inc., Gifu, Japan

7. Fuji Technical Service Center, CLEA Japan, Inc.., Shizuoka, Japan

Funder

Platform Project for Supporting Drug Discovery and Life Science Research [Basis for Supporting Innovative Drug Discovery and Life Science Research (BINDS)]

AMED

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2020.1871113

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3. Pharmacokinetics of catechol cephalosporins. The effect of incorporating substituents into the catechol moiety on pharmacokinetics in a marmoset model

4. Production of Ibuprofen Acyl Glucosides by Human UGT2B7

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