Comprehensive metabolism study of swertiamarin in rats using ultra high-performance liquid chromatography coupled with Quadrupole-Exactive Orbitrap mass spectrometry
Author:
Affiliation:
1. School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, China
2. Beijing Institute for Drug Control, Beijing, China
3. Beijing Tongrentang Research Institute, Beijing, China
Funder
Chinese Pharmacopoeia Commission
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2020.1869856
Reference36 articles.
1. A systematic strategy for rapid identification of chlorogenic acids derivatives in Duhaldea nervosa using UHPLC-Q-Exactive Orbitrap mass spectrometry
2. The anti-inflammation, anti-oxidative and anti-fibrosis properties of swertiamarin in cigarette smoke exposure-induced prostate dysfunction in rats
3. Protective Effect of Gentianine, a compound from Du Huo Ji Sheng Tang, against Freund’s Complete Adjuvant-Induced Arthritis in Rats
4. A UHPLC-HRMS based metabolomics and chemoinformatics approach to chemically distinguish ‘super foods’ from a variety of plant-based foods
5. Synthesis of gentianine N-oxide by enzymatic hydrolysis of swertiamarin in the presence of hydroxylamine and reaction pathway to gentianine and gentianol
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