Preclinical evaluation of saroglitazar magnesium, a dual PPAR-α/γ agonist for treatment of dyslipidemia and metabolic disorders-Reference-Cited by-同舟云学术

Preclinical evaluation of saroglitazar magnesium, a dual PPAR-α/γ agonist for treatment of dyslipidemia and metabolic disorders

Published:2017-12-22 Issue:12 Volume:48 Page:1268-1277
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Patel Harilal¹,Giri Poonam¹,Patel Prakash¹,Singh Sanjay¹,Gupta Laxmikant¹,Patel Urvesh¹,Modi Nirav¹,Shah Kalpesh²,Jain Mukul R.³,Srinivas Nuggehally R.¹,Patel Pankaj¹²³

Affiliation:

1. Department of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Cadila Healthcare Limited , Ahmedabad , India ,

2. Department of Medicinal Chemistry, Zydus Research Centre, Cadila Healthcare Limited , Ahmedabad , India , and

3. Department of Pharmacology and Toxicology, Zydus Research Centre, Cadila Healthcare Limited , Ahmedabad , India

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2017.1413264

Reference17 articles.

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3. Novel Peroxisome Proliferator-activated Receptor (PPAR) γ and PPARδ Ligands Produce Distinct Biological Effects

4. High-throughput cytochrome P450 (CYP) inhibition screening via a cassette probe-dosing strategy. VI. Simultaneous evaluation of inhibition potential of drugs on human hepatic isozymes CYP2A6, 3A4, 2C9, 2D6 and 2E1

5. Rosiglitazone activation of PPARγ-dependent pathways is neuroprotective in human neural stem cells against amyloid-beta–induced mitochondrial dysfunction and oxidative stress

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