A comprehensive analysis of six forms of cytochrome P450 2C (CYP2C) in pigs-Reference-Cited by-同舟云学术

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A comprehensive analysis of six forms of cytochrome P450 2C (CYP2C) in pigs

Published:2022-11-02 Issue:9-11 Volume:52 Page:963-972
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Uno Yasuhiro¹^ORCID,Morikuni Saho²,Shiraishi Mitsuya¹,Asano Atsushi¹,Kawaguchi Hiroaki³,Murayama Norie²,Yamazaki Hiroshi²^ORCID

Affiliation:

1. Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima-city, Japan

2. Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Japan

3. School of Veterinary Medicine, Kitasato University, Towada, Japan

Funder

Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research

Ito Foundation

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2022.2148139

Reference31 articles.

1. Cytochrome P450 Pig Liver Pie: Determination of Individual Cytochrome P450 Isoform Contents in Microsomes from Two Pig Livers Using Liquid Chromatography in Conjunction with Mass Spectrometry

2. Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli.

3. Hepatic Cytochrome P450 Abundance and Activity in the Developing and Adult Göttingen Minipig: Pivotal Data for PBPK Modeling

4. Clinical relevance of genetic polymorphisms in the human CYP2C subfamily

5. Substrate recognition sites in cytochrome P450 family 2 (CYP2) proteins inferred from comparative analyses of amino acid and coding nucleotide sequences.

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1. A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models;Biochemical Pharmacology;2024-03

2. Identification of cytochrome P450 2C18 and 2C76 in tree shrews: P450 2C18 effectively oxidizes typical human P450 2C9/2C19 chiral substrates warfarin and omeprazole with less stereoselectivity;Biochemical Pharmacology;2023-12

3. Newly identified cytochrome P450 3A genes of tree shrews and pigs are expressed and encode functional enzymes;Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology;2023-05

4. Natural Antioxidant By-Product Mixture Counteracts the Effects of Aflatoxin B1 and Ochratoxin A Exposure of Piglets after Weaning: A Proteomic Survey on Liver Microsomal Fraction;Toxins;2023-04-19

5. Novel Cytochrome P450 2C94 Functionally Metabolizes Diclofenac and Omeprazole in Dogs;Drug Metabolism and Disposition;2023-02-08

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