Effects of CYP3A4*1G and CYP3A5*3 polymorphisms on pharmacokinetics of tylerdipine hydrochloride in healthy Chinese subjects-Reference-Cited by-同舟云学术

Effects of CYP3A4*1G and CYP3A5*3 polymorphisms on pharmacokinetics of tylerdipine hydrochloride in healthy Chinese subjects

Published:2018-03-28 Issue:3 Volume:49 Page:375-380
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Zhou Sufeng¹,Tao Mingxue²,Wang Yuanyuan¹,Wang Lu¹,Xie Lijun¹,Chen Juan¹,Zhao Yuqing¹,Liu Yun¹,Zhang Hongwen¹,Ou Ning¹,Wang Guangji²,Shao Feng¹,Aa Jiye²

Affiliation:

1. Phase I Clinical Trial Unit, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China;

2. Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China

Funder

XuanZhu Pharma Co., Ltd.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2018.1447711

Reference27 articles.

1. Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductase

2. Heterogeneity of L- and T-Channels in the Vasculature

3. Significance of the Minor Cytochrome P450 3A Isoforms

4. Pharmacogenomics — Drug Disposition, Drug Targets, and Side Effects

5. CYP3A4*1G polymorphism is associated with lipid-lowering efficacy of atorvastatin but not of simvastatin

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