Intestinal phase-II metabolism of quercetin in HT29 cells, 3D human intestinal tissues and in healthy volunteers: a qualitative comparison using LC-IMS-MS and LC-HRMS-Reference-Cited by-同舟云学术

Intestinal phase-II metabolism of quercetin in HT29 cells, 3D human intestinal tissues and in healthy volunteers: a qualitative comparison using LC-IMS-MS and LC-HRMS

Published:2018-09-28 Issue:8 Volume:49 Page:945-952
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Chalet Clément¹²^ORCID,Hollebrands Boudewijn¹,Duchateau Guus S.¹,Augustijns Patrick²^ORCID

Affiliation:

1. Unilever R&D, Vlaardingen, The Netherlands;

2. Drug Delivery and Disposition, KU Leuven, Leuven, Belgium

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2018.1509246

Reference43 articles.

1. Human Primary Cell-Based Organotypic Microtissues for Modeling Small Intestinal Drug Absorption

2. Mind the gap—deficits in our knowledge of aspects impacting the bioavailability of phytochemicals and their metabolites—a position paper focusing on carotenoids and polyphenols

3. Gene Expression Profiling of Systems Involved in the Metabolism and the Disposition of Xenobiotics: Comparison between Human Intestinal Biopsy Samples and Colon Cell Lines

4. Caco-2 cells - expression, regulation and function of drug transporters compared with human jejunal tissue

5. Computational Studies of the Regioselectivities of COMT-Catalyzed Meta-/Para-O Methylations of Luteolin and Quercetin

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