Antiretroviral concentrations and surrogate measures of efficacy in the brain tissue and CSF of preclinical species-Reference-Cited by-同舟云学术

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Antiretroviral concentrations and surrogate measures of efficacy in the brain tissue and CSF of preclinical species

Published:2018-12-17 Issue:10 Volume:49 Page:1192-1201
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Srinivas Nithya¹,Rosen Elias P.¹,Gilliland Jr William M.¹,Kovarova Martina²,Remling-Mulder Leila³,De La Cruz Gabriela²,White Nicole¹,Adamson Lourdes⁴,Schauer Amanda P.¹,Sykes Craig¹,Luciw Paul⁴,Garcia J. Victor²,Akkina Ramesh³,Kashuba Angela D. M.¹

Affiliation:

1. Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA;

2. School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA;

3. School of Medicine, Colorado State University, Fort Collins, CO, USA;

4. School of Medicine, University of California at Davis, Davis, CA, USA

Funder

NIH

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California National Primate Research Center

Royster Society of Fellows

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2018.1539278

Reference57 articles.

1. Novel Method To Assess Antiretroviral Target Trough Concentrations UsingIn VitroSusceptibility Data

2. Role and modulation of drug transporters in HIV-1 therapy

3. Dementia and Neurocognitive Disorders Due to HIV-1 Infection

4. Mapping of the Allosteric Site in Cholesterol Hydroxylase CYP46A1 for Efavirenz, a Drug That Stimulates Enzyme Activity

5. Protein-Free Efavirenz Concentrations in Cerebrospinal Fluid and Blood Plasma Are Equivalent: Applying the Law of Mass Action To Predict Protein-Free Drug Concentration

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