Microbial biotransformation – an important tool for the study of drug metabolism-Reference-Cited by-同舟云学术

Microbial biotransformation – an important tool for the study of drug metabolism

Published:2018-09-21 Issue:8 Volume:49 Page:877-886
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Salter Rhys¹,Beshore Douglas C.²,Colletti Steven L.³,Evans Liam⁴,Gong Yong¹,Helmy Roy⁵,Liu Yong⁶,Maciolek Cheri M.⁷,Martin Gary⁸,Pajkovic Natasa⁷,Phipps Richard⁴,Small James²,Steele Jonathan⁴,de Vries Ronald⁹,Williams Headley¹⁰,Martin Iain J.¹¹

Affiliation:

1. Department of Preclinical Development and Safety, Janssen Research and Development LLC, Spring House, PA, USA;

2. Department of Global Chemistry, Merck & Co., Inc., West Point, PA, USA;

3. Department of Global Chemistry, Merck & Co., Inc., Kenilworth, NJ, USA;

4. Hypha Discovery Ltd., Berkshire, UK;

5. Department of Pharmacokinetics, Pharmacokinetics and Drug Metabolism, Merck & Co., Inc., Kenilworth, NJ, USA;

6. Department of Preclinical Development, Merck & Co., Inc., West Point, PA, USA;

7. Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism, Merck & Co., Inc., West Point, PA, USA;

8. Department of Global Chemistry, Merck & Co., Inc., Rahway, NJ, USA;

9. Department of Preclinical Development and Safety, Janssen Pharmaceutica, Beerse, Belgium;

10. Colwell Canada Corp., Toronto, Canada;

11. Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism, Merck & Co., Inc., Boston, MA, USA

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2018.1512018

Reference38 articles.

1. Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans

2. Discovery of 1-Butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1H)-pyridone (JNJ-40411813): A Novel Positive Allosteric Modulator of the Metabotropic Glutamate 2 Receptor

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