Evaluation of the pharmacokinetics, tissue distribution and excretion studies of YMR-65, a tubulin polymerization inhibitor with potential anticancer activity, in rats using UPLC-MS/MS-Reference-Cited by-同舟云学术

Evaluation of the pharmacokinetics, tissue distribution and excretion studies of YMR-65, a tubulin polymerization inhibitor with potential anticancer activity, in rats using UPLC-MS/MS

Published:2017-11-10 Issue:9 Volume:48 Page:920-926
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Fan Ali¹,Zhang Yaliang²,Zhang Qing¹,Wei Jiali¹,Lu Xiaoyu¹,Ren Guanghui¹,Zhao Di¹,Li Ning¹,Zhu Hailiang²,Chen Xijing¹

Affiliation:

1. Clinical Pharmacokinetics Laboratory, China Pharmaceutical University, Nanjing, P.R. China and

2. State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, P.R. China

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2017.1380865

Reference24 articles.

1. Endowing Indole-Based Tubulin Inhibitors with an Anchor for Derivatization: Highly Potent 3-Substituted Indolephenstatins and Indoleisocombretastatins

2. New tubulin targeting agents currently in clinical development

3. Cancer treatment and survivorship statistics, 2014

4. Structural Basis for the Interaction of Tubulin with Proteins and Drugs that Affect Microtubule Dynamics

5. Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents

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