Endowing Indole-Based Tubulin Inhibitors with an Anchor for Derivatization: Highly Potent 3-Substituted Indolephenstatins and Indoleisocombretastatins-Reference-Cited by-同舟云学术

Endowing Indole-Based Tubulin Inhibitors with an Anchor for Derivatization: Highly Potent 3-Substituted Indolephenstatins and Indoleisocombretastatins

Published:2013-03-20 Issue:7 Volume:56 Page:2813-2827
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Álvarez Raquel¹,Puebla Pilar¹,Díaz J. Fernando²,Bento Ana C.³,García-Navas Rósula³,de la Iglesia-Vicente Janis³,Mollinedo Faustino³,Andreu José Manuel²,Medarde Manuel¹,Peláez Rafael¹

Affiliation:

1. Laboratorio de Química Orgánica y Farmacéutica, CIETUS and IBSAL, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, E-37007 Salamanca, Spain

2. Centro de Investigaciones Biológicas, CSIC, Madrid 28040, Spain

3. Instituto de Biología Molecular y Celular del Cáncer, Centro de Investigación del Cáncer, CSIC-Universidad de Salamanca, Campus Miguel de Unamuno, E-37007 Salamanca, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3015603

Reference56 articles.

1. Structural Plasticity in Actin and Tubulin Polymer Dynamics

2. Drugs that target dynamic microtubules: A new molecular perspective

3. Microtubule-binding agents: a dynamic field of cancer therapeutics

4. Microtubule dynamics as a target in oncology

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