Stereoselective pharmacokinetic study of rhynchophylline and isorhynchophylline epimers in rat plasma by liquid chromatography–tandem mass spectrometry-Reference-Cited by-同舟云学术

Stereoselective pharmacokinetic study of rhynchophylline and isorhynchophylline epimers in rat plasma by liquid chromatography–tandem mass spectrometry

Published:2016-07-07 Issue:6 Volume:47 Page:479-487
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Wang Xin¹,Zheng Mei¹,Liu Jia²,Qiao Zhou¹,Liu Wenyuan¹³,Feng Feng⁴

Affiliation:

1. Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China,

2. Pharmic Laboratory Animal Center, China Pharmaceutical University, Nanjing, China,

3. Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, China, and

4. Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing, China

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2016.1203043

Reference27 articles.

1. Drug disposition in three dimensions: an update on stereoselectivity in pharmacokinetics

2. Determination of Rhynchophylline in Rat Plasma by Liquid Chromatography Mass Spectrometry and Its Application

3. Urinary metabolites of isorhynchophylline in rats and their neuroprotective activities in the HT22 cell assay

4. Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer’s disease

5. Uncaria rhynchophylla, a Chinese medicinal herb, has potent antiaggregation effects on Alzheimer's β-amyloid proteins

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