Pharmacokinetic study on hirsutine and hirsuteine in rats using UPLC–MS/MS-Reference-Cited by-同舟云学术

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Pharmacokinetic study on hirsutine and hirsuteine in rats using UPLC–MS/MS

Published:2019-06 Issue:2 Volume:31 Page:99-104
ISSN:2083-5736
Container-title:Acta Chromatographica
language:en
Short-container-title:Acta Chromatographica

Author:

Han Aixia¹,Lin Guanyang²,Cai Jinzhang³,Wu Qing²,Geng Peiwu¹,Ma Jianshe⁴,Wang Xianqin⁴,Lin Chongliang²

Affiliation:

1. Department of Pharmacy, The People's Hospital of Lishui, Lishui 323000, China

2. Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China

3. The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325027, China

4. Analytical and Testing Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China

Publisher

Akademiai Kiado Zrt.

Subject

General Chemistry

Link

https://www.akademiai.com/doi/pdf/10.1556/1326.2017.00365

Reference37 articles.

1. A review on indole alkaloids isolated from Uncaria rhynchophylla and their pharmacological studies

2. Chemical and biological comparison of different sections of Uncaria rhynchophylla (Gou-Teng)

3. Protective effects on vascular endothelial cell in N'-nitro-L-arginine (L-NNA)-induced hypertensive rats from the combination of effective components of Uncaria rhynchophylla and Semen Raphani

4. Alkaloids from the hook-bearing branch ofUncariarhynchophyllaand their neuroprotective effects against glutamate-induced HT22 cell death

5. Uncaria rhynchophylla and rhynchophylline improved kainic acid-induced epileptic seizures via IL-1β and brain-derived neurotrophic factor

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1. Preclinical pharmacokinetic studies of villocarine A, an active Uncaria alkaloid;Drug Testing and Analysis;2024-05-15

2. Metabolites identification and pharmacokinetic profile of hirsuteine, a bioactive component in Uncaria in rats by ultra‐high performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry;Journal of Separation Science;2022-10-10

3. Properties, Pharmacology, and Pharmacokinetics of Active Indole and Oxindole Alkaloids in Uncaria Hook;Frontiers in Pharmacology;2021-07-14

4. Development and validation of a rapid UHPLC-MS/MS method for the determination of fenofibric acid in human plasma: Application to a pharmacokinetic study of fenofibrate tablet in Chinese subjects;Acta Chromatographica;2021-06-09

5. Pharmacokinetic Study of Zhebeirine in Mouse Blood by Ultra- Performance Liquid Chromatography/tandem Mass Spectrometry;Current Pharmaceutical Analysis;2021-04

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