Determination of enzymatic kinetics of metabolism of dimethoate and omethoate in rats and humans
Author:
Affiliation:
1. FMC Corporation, Philadelphia, PA, USA
2. Frontage Laboratories Inc, Exton, PA, USA
3. Exponent, Alexandria, VA, USA
Funder
FMC Corporation
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2023.2228904
Reference17 articles.
1. Evidences for CYP3A4 autoactivation in the desulfuration of dimethoate by the human liver
2. Kinetic parameters of OPT pesticide desulfuration by c-DNA expressed human CYPs
3. CYP-specific bioactivation of four organophosphorothioate pesticides by human liver microsomes
4. Animal Metabolism of Insecticides, Bovine Metabolism of Organophosphorus Insecticides. Metabolism and Residues Associated with Oral Administration of Dimethoate to Rats and Three Lactating Cows
5. Metabolism of organophosphorus insecticides—XI
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1. A physiologically-based pharmacokinetic/pharmacodynamic (PBPK/PD) model for the insecticide dimethoate;Xenobiotica;2023-05-04
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