A physiologically-based pharmacokinetic/pharmacodynamic (PBPK/PD) model for the insecticide dimethoate

Author:

Reiss Richard1,Loccisano Anne1,Deines Andrew2,Kim Myoungwoo3,Nallani Gopinath3,Chandrasekaran Appavu3,Whatling Paul3

Affiliation:

1. Exponent, Alexandria, VA, USA

2. Exponent, Bellevue, Washington, DC, USA

3. FMC Corporation, Philadelphia, PA, USA

Funder

FMC Corporation

.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Reference48 articles.

1. A Multiple-Path Model of Particle Deposition in the Rat Lung

2. Correlating in vitro data to in vivo findings for risk assessment

3. Barnett J. 2012a. Oral gavage acute dose time of peak effect cholinesterase depression study of omethoate in neonatal and adult rats: final report. Horsham (PA): Charles River Laboratories. Report Number: 20010314.

4. Barnett J. 2012b. Oral gavage acute dose comparative cholinesterase study of omethoate in neonatal and adult rats. Horsham (PA): Charles River Laboratories. Project Number: 20010315.

5. Bernal J. 2015a. In-vivo rat skin penetration of 14C-dimethoate in [Dimethoate 400 EC] CHA 3621-04 Test Item. Vergèze (France): Eurofins Agroscience Services Chem SAS. Report No.: S14-04345.

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