Synthesis and evaluation of indomethacin prodrugs with a diester structure that are metabolically activated by human carboxylesterases
Author:
Affiliation:
1. Faculty of Pharmacy, Chiba Institute of Science, Choshi, Chiba, Japan
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2023.2298270
Reference26 articles.
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2. Structural Insights into Drug Processing by Human Carboxylesterase 1: Tamoxifen, Mevastatin, and Inhibition by Benzil
3. Comparison of substrate specificity among human arylacetamide deacetylase and carboxylesterases
4. The Emerging Role of Human Esterases
5. Prilocaine- and Lidocaine-Induced Methemoglobinemia Is Caused by Human Carboxylesterase-, CYP2E1-, and CYP3A4-Mediated Metabolic Activation
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