2-(Naphthalene-2-thio)-5,8-dimethoxy-1,4-naphthoquinone induces apoptosis via ROS-mediated MAPK, AKT, and STAT3 signaling pathways in HepG2 human hepatocellular carcinoma cells-Reference-Cited by-同舟云学术

2-(Naphthalene-2-thio)-5,8-dimethoxy-1,4-naphthoquinone induces apoptosis via ROS-mediated MAPK, AKT, and STAT3 signaling pathways in HepG2 human hepatocellular carcinoma cells

Published:2019-09-06 Issue:1 Volume:45 Page:33-43
ISSN:0148-0545
Container-title:Drug and Chemical Toxicology
language:en
Short-container-title:Drug and Chemical Toxicology

Author:

Liu Yang¹,Luo Ying-Hua²,Li Shu-Mei³,Shen Gui-Nan¹,Wang Jia-Ru¹,Zhang Yi¹,Feng Yu-Chao³,Xu Wan-Ting¹,Zhang Yu¹,Zhang Tong¹,Xue Hui¹,Wang Hong-Xing¹,Cui Yang¹,Wang Ying⁴⁵,Jin Cheng-Hao¹⁴⁵^ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology, College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, China

2. College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, China

3. Hemodialysis Center, Daqing Oilfield General Hospital, Daqing, China

4. College of Food Science and Technology, Heilongjiang Bayi Agricultural University, Daqing, China

5. National Coarse Cereals Engineering Research Center, Daqing, China

Funder

Multigrain Production and Processing Characteristic Discipline Construction Project

Postdoctoral Scientific Research Foundation of Heilongjiang Province of China

National key research and development plan “Regulation and activity retention technology and application of coarse cereals active components in processing”

Publisher

Informa UK Limited

Subject

Chemical Health and Safety,Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/01480545.2019.1658767

Reference44 articles.

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2. Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium

3. Synthesis and evaluation of antitumor activity of 2- and 6-[(1,3-benzothiazol-2-yl)aminomethyl]-5,8-dimethoxy-1,4-naphthoquinone derivatives

4. Tannic acid inhibits the Jak2/STAT3 pathway and induces G1/S arrest and mitochondrial apoptosis in YD-38 gingival cancer cells

5. Putting the pieces together: How is the mitochondrial pathway of apoptosis regulated in cancer and chemotherapy?

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