Rational design of a deuterium-containing M2-S31N channel blocker UAWJ280 with in vivo antiviral efficacy against both oseltamivir sensitive and -resistant influenza A viruses-Reference-Cited by-同舟云学术

Rational design of a deuterium-containing M2-S31N channel blocker UAWJ280 with in vivo antiviral efficacy against both oseltamivir sensitive and -resistant influenza A viruses

Published:2021-01-01 Issue:1 Volume:10 Page:1832-1848
ISSN:2222-1751
Container-title:Emerging Microbes & Infections
language:en
Short-container-title:Emerging Microbes & Infections

Author:

Cáceres C. Joaquín¹^ORCID,Hu Yanmei²,Cárdenas-García Stivalis¹,Wu Xiangmeng²,Tan Haozhou²,Carnaccini Silvia³,Gay L. Claire¹^ORCID,Geiger Ginger¹,Ma Chunlong²,Zhang Qing-Yu²,Rajao Daniela¹,Perez Daniel R.¹^ORCID,Wang Jun²^ORCID

Affiliation:

1. Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, USA

2. Department of Pharmacology and Toxicology, College of Pharmacy, The University of Arizona, Tucson, AZ, USA

3. Tifton diagnostic laboratory, College of Veterinary Medicine, University of Georgia, Tifton, GA, USA

Funder

NIAID-NIH

Center for Research on Influenza Pathogenesis

Centers for Influenza Research and Surveillance

Arizona Biomedical Research Centre

Georgia Research Alliance

Caswell S. Eidson endowment funds

NIH