Effectiveness of inactivated COVID-19 vaccines against mild disease, pneumonia, and severe disease among persons infected with SARS-CoV-2 Omicron variant: real-world study in Jilin Province, China

Author:

Xu Hongqin1,Li Hongyan2,You Hailong3,Zhang Peng4,Li Nan5,Jiang Nan6,Cao Yang7,Qin Ling8,Qin Guixiang9,Qu Hongbo10,Wang Heyuan11,Zou Bo12,He Xia13,Li Dan14,Zhao Huazhong15,Huang Gang16,Li Yang14,Zhang Hefeng15,Zhu Liping17,Qiao Hongmei18,Li Hongjun19,Liu Shurong20,Gu Lina5,Yin Guidong21,Hu Ye20,Xu Songbai22,Guo Weiying11,Wang Nanya23,Liu Chaoying14,Gao Pujun1,Cao Jie24,Zheng Yang8,Zhang Kaiyu4,Wang Yang4,Chen Hui20,Zhang Jian6,Mu Dongmei25,Niu Junqi1

Affiliation:

1. Department of Hepatology, Center of Infectious Diseases and Pathogen Biology, The First Hospital of Jilin University, Changchun, People’s Republic of China

2. Nursing Department, The First Hospital of Jilin University, Changchun, People’s Republic of China

3. Department of Pediatrics, First Hospital of Jilin University, Changchun, People’s Republic of China

4. Department of Infectious Diseases, Center of Infectious Diseases and Pathogen Biology, The First Hospital of Jilin University, Changchun, People’s Republic of China

5. Intensive Care Unit, The First Hospital of Jilin University, Changchun, People’s Republic of China

6. Department of Infectious Diseases, Changchun Infectious Disease Hospital, Changchun, People’s Republic of China

7. Department of obstetrics and gynecology, Hepatobiliary Hospital of Jilin, Changchun, People’s Republic of China

8. Department of Cardiovascular Medicine, The First Hospital of Jilin University, Changchun, People’s Republic of China

9. Center of Tubercular Meningitis, Changchun Infectious Disease Hospital, Changchun, People’s Republic of China

10. Department of Medical Affairs, Hepatobiliary Hospital of Jilin, Changchun, People’s Republic of China

11. Department of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun, People’s Republic of China

12. Department of Medical Affairs, Changchun Infectious Disease Hospital, Changchun, People’s Republic of China

13. Nursing Department, Hepatobiliary Hospital of Jilin, Changchun, People’s Republic of China

14. Department of Respiratory Medicine, The First Hospital of Jilin University, Changchun, People’s Republic of China

15. Department of Integrated Traditional and Western Medicine, Changchun Infectious Disease Hospital, Changchun, People’s Republic of China

16. Center of Information and Statistics, Hepatobiliary Hospital of Jilin, Changchun, People’s Republic of China

17. Department of Integrated Traditional and Western Medicine, Hepatobiliary Hospital of Jilin, Changchun, People’s Republic of China

18. Department of pediatric respiratory medicine, The First Hospital of Jilin University, Changchun, People’s Republic of China

19. The Fifth treatment area, Changchun Infectious Disease Hospital, Changchun, People’s Republic of China

20. Department of Hepatology, Hepatobiliary Hospital of Jilin, Changchun, People’s Republic of China

21. Department of cerebral surgery, Changchun Infectious Disease Hospital, Changchun, People’s Republic of China

22. Department of Neurosurgery, the First Hospital of Jilin University, Changchun, People’s Republic of China

23. Cancer Center, The First Hospital of Jilin University, Changchun, People’s Republic of China

24. Department of Neology, The First Hospital of Jilin University, Changchun, People’s Republic of China

25. Department of Clinical Epidemiology, The First Hospital of Jilin University, Changchun, People’s Republic of China

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

Reference37 articles.

1. Organization WH. (2022). WHO Coronavirus (COVID-19) Dashboard. 2022: https://covid19.who.int/.

2. Organization WH. Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern. 2021: https://www.who.int/news/item/26-11-2021-classification-of-omicron-(b.1.1.529)-sars-cov-2-variant-of-concern.

3. Omicron likely to weaken COVID vaccine protection

4. How bad is Omicron? What scientists know so far

5. SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection

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