Simultaneous Determination of a Novel Antiarrhythmic Agent, 7-Benzyl-3-Thia-7-Azabicyclo[3.3.1]Nonane and Its Sulfoxidation Metabolite in Plasma and Urine by HPLC-Reference-Cited by-同舟云学术

Simultaneous Determination of a Novel Antiarrhythmic Agent, 7-Benzyl-3-Thia-7-Azabicyclo[3.3.1]Nonane and Its Sulfoxidation Metabolite in Plasma and Urine by HPLC

Published:1994-10 Issue:17 Volume:17 Page:3681-3694
ISSN:0148-3919
Container-title:Journal of Liquid Chromatography
language:en
Short-container-title:Journal of Liquid Chromatography

Author:

Chen C. L.,Sangiah S.,Chen H.,Berlin K. D.,Garrison G. L.,Scherlag B. J.,Lazzara R.

Publisher

Informa UK Limited

Subject

Molecular Medicine

Link

http://www.tandfonline.com/doi/pdf/10.1080/10826079408013985

Reference21 articles.

1. Synthesis, conformational analysis, and antiarrhythmic properties of 7-benzyl-3-thia-7-azabicyclo[3.3.1]nonan-9-one, 7-benzyl-3-thia-7-azabicyclo[3.3.1]nonane hydroperchlorate, and 7-benzyl-9-phenyl-3-thia-7-azabicyclo[3.3.1]nonan-9-ol hydroperchlorate and derivatives. Single-crystal x-ray diffraction analysis and evidence for chair-chair and chair-boat conformers in the solid state

2. A study of the synthesis and antiarrhythmic properties of selected 3,7-diheterabicyclo[3.3.1]nonanes with substituents at the 2,4-positions and at the 9-position

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