A study of the synthesis and antiarrhythmic properties of selected 3,7-diheterabicyclo[3.3.1]nonanes with substituents at the 2,4-positions and at the 9-position-Reference-Cited by-同舟云学术

A study of the synthesis and antiarrhythmic properties of selected 3,7-diheterabicyclo[3.3.1]nonanes with substituents at the 2,4-positions and at the 9-position

Published:1990-02 Issue:1 Volume:25 Page:1-8
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Smith Gary Steven,Thompson Mark Daniel,Berlin Kenneth Darrell,Holt Elizabeth Manners,Scherlag Benjamin Jacob,Patterson Eugene,Lazzara Ralph

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference20 articles.

1. Chemistry of 3-azabicyclo[3.3.1]nonanes

2. Synthesis, conformational analysis, and antiarrhythmic properties of 7-benzyl-3-thia-7-azabicyclo[3.3.1]nonan-9-one, 7-benzyl-3-thia-7-azabicyclo[3.3.1]nonane hydroperchlorate, and 7-benzyl-9-phenyl-3-thia-7-azabicyclo[3.3.1]nonan-9-ol hydroperchlorate and derivatives. Single-crystal x-ray diffraction analysis and evidence for chair-chair and chair-boat conformers in the solid state

3. Synthesis and antiarrhythmic properties of novel 3-selena-7-azabicyclo[3.3.1]nonanes and derivatives. Single-crystal x-ray diffraction analysis of 7-benzyl-3-selena-7-azabicyclo[3.3.1]nonan-9-one and 7-benzyl-3-selena-7-azabicyclo[3.3.1]nonane hydroperchlorate

4. Conformation in solution of tetraaryl‐3,7‐diazabicyclo[3.3.1]‐nonanes and tetra‐ and pentaaryl‐1,3‐diazaadamantanes. A nuclear magnetic resonance study

5. Synthese und Struktur diastereomerer 2,4,6,8‐Tetraaryl‐3‐azabicyclo[3.3.1]nonane und ihre Konformation im Kristall und in Lösung. Stereochemie der Mannich‐Reaktion von cis ‐3,5‐Diphenylcyclohexanon und ‐4‐heteracyclohexanonen

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