Synthesis and Antiviral Evaluation of Novel 2′,2′-Difluoro 5′-Norcarbocyclic Phosphonic Acid Nucleosides as Antiviral Agents
Author:
Publisher
Informa UK Limited
Subject
Genetics,Molecular Medicine,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1080/15257770.2013.854380
Reference27 articles.
1. Recent advances in the synthesis of fluorinated nucleosides
2. Synthesis and anti-HIV activity of GS-9148 (2′-Fd4AP), a novel nucleoside phosphonate HIV reverse transcriptase inhibitor
3. Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148
4. Design and Profiling of GS-9148, a Novel Nucleotide Analog Active against Nucleoside-Resistant Variants of Human Immunodeficiency Virus Type 1, and Its Orally Bioavailable Phosphonoamidate Prodrug, GS-9131
5. Synthesis of 2-deoxy-2,2-difluoro-D-ribose and 2-deoxy-2,2'-difluoro-D-ribofuranosyl nucleosides
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2. Synthesis and antibacterial activity of 5′-tetrachlorophthalimido and 5′-azido 5′-deoxyribonucleosides;Nucleosides, Nucleotides & Nucleic Acids;2017-01-03
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4. Recent progress for the synthesis of selected carbocyclic nucleosides;Future Medicinal Chemistry;2015-09
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