N6-methyl adenosine in siRNA evades immune response without reducing RNAi activity
Author:
Affiliation:
1. Graduate School of Science, Nagoya University, Nagoya, Japan;
2. Research Center for Materials Science, Nagoya University, Nagoya, Japan;
3. JST CREST, Science and Technology Agency, Tokyo, Japan
Funder
JSPS KAKENHI
Publisher
Informa UK Limited
Subject
Genetics,Molecular Medicine,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/15257770.2019.1641205
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1. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
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4. Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
5. Safety of antisense oligonucleotide and siRNA-based therapeutics
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