Is there enough focus on lipophilicity in drug discovery?
Author:
Affiliation:
1. Department of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA, USA
Publisher
Informa UK Limited
Subject
Drug Discovery
Link
https://www.tandfonline.com/doi/pdf/10.1080/17460441.2020.1691995
Reference17 articles.
1. Innovation in the pharmaceutical industry: New estimates of R&D costs
2. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
3. The Impact of Lipophilicity in Drug Discovery: Rapid Measurements by Means of Reversed-Phase HPLC
4. Lipophilicity and biomimetic properties to support drug discovery
5. The influence of the 'organizational factor' on compound quality in drug discovery
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