Introduction to biological complexity as a missing link in drug discovery
Author:
Affiliation:
1. AbbVie, Department of Integrative Pharmacology, Integrated Science and Technology, North Chicago, IL, USA
2. Molecular Cardiology, Institute of Life Sciences, Swansea University Medical School, Swansea, Wales, UK
Funder
British Heart Foundation
Biotechnology and Biological Sciences Research Council (BBSRC)
Wellcome Trust
Publisher
Informa UK Limited
Subject
Drug Discovery
Link
https://www.tandfonline.com/doi/pdf/10.1080/17460441.2018.1480608
Reference77 articles.
1. Searching for new cardiovascular drugs: towards improved systems for drug screening?
2. Evolution of strategies to improve preclinical cardiac safety testing
3. iPSC Disease Modeling
4. Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform
5. Stem cell–derived models to improve mechanistic understanding and prediction of human drug‐induced liver injury
Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Non-thermal disruption of β-adrenergic receptor-activated Ca2+ signalling and apoptosis in human ES-derived cardiomyocytes by microwave electric fields at 2.4 GHz;Biochemical and Biophysical Research Communications;2023-06
2. Network modeling helps to tackle the complexity of drug–disease systems;WIREs Mechanisms of Disease;2023-03-23
3. Anticancer activity and metabolic profile alterations by ortho‐topolin riboside in in vitro and in vivo models of non‐small cell lung cancer;The FASEB Journal;2022-01-23
4. Single-Target Versus Multi-Target Drugs Versus Combinations of Drugs With Multiple Targets: Preclinical and Clinical Evidence for the Treatment or Prevention of Epilepsy;Frontiers in Pharmacology;2021-10-27
5. How necessary are animal models for modern drug discovery?;Expert Opinion on Drug Discovery;2021-09-03
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3