Rapid oral transmucosal delivery of zaleplon–lavender oil utilizing self-nanoemulsifying lyophilized tablets technology: development, optimization and pharmacokinetic evaluation

Author:

Ali Sarah A.1,Alhakamy Nabil A.23ORCID,Hosny Khaled M.2ORCID,Alfayez Eman4,Bukhary Deena M.5,Safhi Awaji Y.6,Badr Moutaz Y.5,Mushtaq Rayan Y.7,Alharbi Majed8,Huwaimel Bader9,Alissa Mohammed10,Alshehri Sameer11,Alamri Ali H.12,Alqahtani Taha13

Affiliation:

1. Department of Oral Diagnostic Sciences, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia

2. Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia

3. Center of Excellence for Drug Research and Pharmaceutical Industries, King Abdulaziz University, Jeddah, Saudi Arabia

4. Department of Oral Biology, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia

5. Department of Pharmaceutics, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia

6. Department of Pharmaceutics, College of Pharmacy, Jazan University, Jazan, Saudi Arabia

7. Department of Pharmaceutics, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia

8. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia

9. Department of Pharmaceutical Chemistry, College of Pharmacy, University of Ha’il, Ha’il, Saudi Arabia

10. Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia

11. Department of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Taif University, Taif, Saudi Arabia

12. Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha, Saudi Arabia

13. Department of Pharmacology, College of Pharmacy, King Khalid University, Abha, Saudi Arabia

Funder

Deanship of Scientific Research (DSR) at King Abdulaziz University, Jeddah

Publisher

Informa UK Limited

Subject

Pharmaceutical Science,General Medicine

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