Electrospun polymer fibers modified with FK506 for the long-term treatment of acute cardiac allograft rejection in a heart transplantation model-Reference-Cited by-同舟云学术

Electrospun polymer fibers modified with FK506 for the long-term treatment of acute cardiac allograft rejection in a heart transplantation model

Published:2023 Issue:11 Volume:11 Page:4032-4042
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Deng Cheng¹²³,Jin Qiaofeng¹²³,Xu Jia¹²³,Fu Wenpei¹²³,He Mengrong¹²³,Xu Lingling¹²³,Song Yishu¹²³,Wang Wenyuan¹²³,Yi Luyang¹²³,Chen Yihan¹²³,Gao Tang¹²³,Wang Jing¹²³,Lv Qing¹²³,Yang Yali¹²³,Zhang Li¹²³,Xie Mingxing¹²³^ORCID

Affiliation:

1. Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China

2. Hubei Province Clinical Research Center for Medical Imaging, Wuhan, 430022, China

3. Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China

Abstract

A schematic diagram of an electrospinning device for PCL-FK506 microfibers. PCL-FK506 microfibers was applied in abdominal heterotopic heart transplantation model and its effects on survival time, immune response and secretion of cytokine.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D3BM00374D

Reference47 articles.

1. Honoring 50 Years of Clinical Heart Transplantation in Circulation

2. Adherence to immunosuppression in adult heart transplant recipients: A systematic review

3. Clinical translation of long-acting drug delivery formulations

4. Injectable implants for the sustained release of protein and peptide drugs

5. A review of existing strategies for designing long-acting parenteral formulations: Focus on underlying mechanisms, and future perspectives

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