Capture and display of antibodies secreted by hybridoma cells enables fluorescent on-cell screening
Author:
Affiliation:
1. Lankenau Institute for Medical Research, Wynnewood, PA, USA
2. Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA
3. Division of Neurology, Children’s Hospital of Pennsylvania, Philadelphia, PA, USA
Funder
National Cancer Institute
National Institute of Allergy and Infectious Diseases
National Institute of Neurological Disorders and Stroke
World Health Organization
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2019.1574520
Reference43 articles.
1. Continuous cultures of fused cells secreting antibody of predefined specificity
2. Use of Human Hybridoma Technology To Isolate Human Monoclonal Antibodies
3. Phage display and hybridoma generation of antibodies to human CXCR2 yields antibodies with distinct mechanisms and epitopes
4. Discovery and bio-optimization of human antibody therapeutics using the XenoMouse®transgenic mouse platform
5. Solubility evaluation of murine hybridoma antibodies
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