Impact of linker-drug on ion exchange chromatography separation of antibody-drug conjugates
Author:
Affiliation:
1. Process Analytical Chemistry, AbbVie Inc., North Chicago, IL, USA
Funder
AbbVie
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://tandfonline.com/doi/pdf/10.1080/19420862.2019.1628589
Reference30 articles.
1. Characterization of Cysteine-Linked Conjugation Profiles of Immunoglobulin G1 and Immunoglobulin G2 Antibody–Drug Conjugates
2. Profiling Antibody Drug Conjugate Positional Isomers: A System-of-Equations Approach
3. Reduction−Alkylation Strategies for the Modification of Specific Monoclonal Antibody Disulfides
4. Antibody-drug conjugate model fast characterization by LC-MS following IdeS proteolytic digestion
5. Characterization of antibody drug conjugate positional isomers at cysteine residues by peptide mapping LC–MS analysis
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