Specific and high-resolution identification of monoclonal antibody fragments detected by capillary electrophoresis–sodium dodecyl sulfate using reversed-phase HPLC with top-down mass spectrometry analysis
Author:
Affiliation:
1. Bio Therapeutics Development, Janssen Research & Development, LLC, Malvern, PA, USA
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2019.1646554
Reference33 articles.
1. Fragmentation of monoclonal antibodies
2. Therapeutic Monoclonal Antibodies
3. Therapeutic monoclonal antibodies for respiratory diseases: Current challenges and perspectives, March 31 – April 1, 2016, Tours, France
4. Development of orthogonal NISTmAb size heterogeneity control methods
5. Xu Y, Wang D, Mason B, Rossomando T, Li N, Liu D, Cheung JK, Xu W, Raghava S, Katiyar A, et al. Structure, heterogeneity and developability assessment of therapeutic antibodies. MAbs. 2019 Feb/Mar;11(2):239–264.
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