Structure, heterogeneity and developability assessment of therapeutic antibodies

Author:

Xu Yingda1,Wang Dongdong2,Mason Bruce3,Rossomando Tony3,Li Ning4,Liu Dingjiang5ORCID,Cheung Jason K6,Xu Wei7,Raghava Smita8,Katiyar Amit9,Nowak Christine3,Xiang Tao10,Dong Diane D.10,Sun Joanne11,Beck Alain12,Liu Hongcheng3

Affiliation:

1. Protein Analytics, Adimab, Lebanon, NH, USA

2. Analytical Department, Bioanalytix, Inc., Cambridge, MA, USA

3. Product Characterization, Alexion Pharmaceuticals, Inc., New Haven, CT, USA

4. Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA

5. Formulation Development, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA

6. Pharmaceutical Sciences, MRL, Merck & Co., Inc., Kenilworth, NJ, USA

7. Analytical Method Development, MRL, Merck & Co., Inc., Kenilworth, NJ, USA

8. Sterile Formulation Sciences, MRL, Merck & Co., Inc., Kenilworth, NJ, USA

9. Analytical Development, Bristol-Myers Squibb, Pennington, NJ, USA

10. Manufacturing Sciences, Abbvie Bioresearch Center, Worcester, MA, USA

11. Product development, Innovent Biologics, Suzhou Industrial Park, China

12. Analytical chemistry, NBEs, Center d’immunologie Pierre Fabre, St Julien-en-Genevois Cedex, France

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

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