Evidence for intermolecular domain exchange in the Fab domains of dimer and oligomers of an IgG1 monoclonal antibody
Author:
Affiliation:
1. Analytical Research and Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc., Andover, USA
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2017.1331803
Reference32 articles.
1. Effects of protein aggregates: An immunologic perspective
2. Antibody Production to Aggregated Human γg-Globulin in Acquired Hypogammaglobulinemia
3. Highly Aggregated Antibody Therapeutics Can Enhance the in Vitro Innate and Late-stage T-cell Immune Responses
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