Enrichment strategy and initial characterization of heterodimers enriched from a co-formulated cocktail of therapeutic antibodies against SARS-COV-2-Reference-Cited by-同舟云学术

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Enrichment strategy and initial characterization of heterodimers enriched from a co-formulated cocktail of therapeutic antibodies against SARS-COV-2

Published:2024-04-09 Issue:1 Volume:16 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Liu Sophia¹,Yan Yuetian²,Secor Cody M.¹,Oberholtzer Zachary R.¹,Skow Donna J.³,Sheikh Mushhood³,Moon Youmi¹,Fu Yue¹,Sandu Cristinel³,Wang Shunhai²,Li Ning²,Nguyen Jennifer B.¹,Rosconi Michael P.¹,Pyles Erica A.¹

Affiliation:

1. Protein Biochemistry, Regeneron Pharmaceuticals, Inc ., Tarrytown, NY, USA

2. Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA

3. Therapeutic Proteins, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA

Funder

there is no funding

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2024.2338301

Reference26 articles.

1. Analytical characterization of coformulated antibodies as combination therapy

2. Advancements in the co-formulation of biologic therapeutics

3. Evaluating and Mitigating the Immunogenicity of Therapeutic Proteins

4. Post-Column Denaturation-Assisted Native Size-Exclusion Chromatography–Mass Spectrometry for Rapid and In-Depth Characterization of High Molecular Weight Variants in Therapeutic Monoclonal Antibodies

5. Immunostimulatory monoclonal antibodies for cancer therapy

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