Beyond bispecificity: Controlled Fab arm exchange for the generation of antibodies with multiple specificities-Reference-Cited by-同舟云学术

Beyond bispecificity: Controlled Fab arm exchange for the generation of antibodies with multiple specificities

Published:2022-01-11 Issue:1 Volume:14 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Yanakieva Desislava¹²,Pekar Lukas²,Evers Andreas²,Fleischer Markus³,Keller Stephan³,Mueller-Pompalla Dirk³,Toleikis Lars²,Kolmar Harald¹,Zielonka Stefan²,Krah Simon²

Affiliation:

1. Institute for Organic Chemistry and Biochemistry, Technische Universität Darmstadt, Darmstadt, Germany

2. Protein Engineering and Antibody Technologies, Protein Engineering and Antibody Technologies, Merck Healthcare KGaA, Darmstadt, Germany

3. Protein and Cell Sciences, Merck Healthcare KGaA, Darmstadt, Germany

Funder

The author(s) reported there is no funding associated with the work featured in this article

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2021.2018960

Reference49 articles.

1. Continuous cultures of fused cells secreting antibody of predefined specificity

2. Hybridoma Technology for the Generation of Monoclonal Antibodies

3. FDA approves 100th monoclonal antibody product

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