Differences in human IgG1 and IgG4 S228P monoclonal antibodies viscosity and self-interactions: Experimental assessment and computational predictions of domain interactions-Reference-Cited by-同舟云学术

Differences in human IgG1 and IgG4 S228P monoclonal antibodies viscosity and self-interactions: Experimental assessment and computational predictions of domain interactions

Published:2021-01-01 Issue:1 Volume:13 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Lai Pin-Kuang¹²,Ghag Gaurav³,Yu Yao³,Juan Veronica³,Fayadat-Dilman Laurence³,Trout Bernhardt L.¹

Affiliation:

1. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts USA

2. Current Address: Department of Chemical Engineering and Materials Science, Stevens Institute of Technology, Hoboken, New Jersey USA

3. Merck & Co, Discovery Biologics, Protein Sciences Department, South San Francisco, CA , USA

Funder

funding

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2021.1991256

Reference48 articles.

1. IgG Subclasses and Allotypes: From Structure to Effector Functions

2. The Increasingly Human and Profitable Monoclonal Antibody Market

3. The Antibody Society. Therapeutic monoclonal antibodies approved or in review in the EU or US. [accessed 2021 Mar 21]. https://www.antibodysociety.org/antibody-therapeutics-product-data/

4. When binding is enough: nonactivating antibody formats

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