Reduction of monoclonal antibody viscosity using interpretable machine learning

Author:

Makowski Emily K.12,Chen Hsin-Ting23,Wang Tiexin23,Wu Lina23,Huang Jie12,Mock Marissa4,Underhill Patrick5,Pelegri-O’Day Emma4,Maglalang Erick6,Winters Dwight4,Tessier Peter M.1237ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA

2. Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA

3. Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA

4. Therapeutic Discovery, Research, Amgen Inc, Thousand Oaks, CA, USA

5. Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA

6. Drug Product Technologies, Amgen Inc, Thousand Oaks, CA, USA

7. Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA

Funder

National Institutes of Health

National Science Foundation

University of Michigan

Rackham Graduate Fellowship and Albert M. Mattocks Chair

Publisher

Informa UK Limited

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