A minimal physiologically based pharmacokinetic model to characterize colon TNF suppression and treatment effects of an anti-TNF monoclonal antibody in a mouse inflammatory bowel disease model-Reference-Cited by-同舟云学术

A minimal physiologically based pharmacokinetic model to characterize colon TNF suppression and treatment effects of an anti-TNF monoclonal antibody in a mouse inflammatory bowel disease model

Published:2020-01-01 Issue:1 Volume:12 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Zheng Songmao¹,Niu Jin¹²,Geist Brian¹,Fink Damien¹,Xu Zhenhua³,Zhou Honghui³,Wang Weirong³

Affiliation:

1. Biologics Development Sciences, Janssen BioTherapeutics (JBIO), Spring House, PA, USA

2. Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA

3. Clinical Pharmacology and Pharmacometrics, Quantitative Sciences, Spring House, PA, USA

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2020.1813962

Reference43 articles.

1. Clinical Aspects and Pathophysiology of Inflammatory Bowel Disease

2. Immunopathogenesis of IBD: current state of the art

3. Role of biologics and biosimilars in inflammatory bowel disease: current trends and future perspectives

4. Management of Inflammatory Bowel Disease with Infliximab and Other Anti-Tumor Necrosis Factor Alpha Therapies

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