The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity-Reference-Cited by-同舟云学术

The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity

Published:2015-02-06 Issue:2 Volume:7 Page:331-343
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Abdiche Yasmina Noubia,Yeung Yik Andy,Chaparro-Riggers Javier,Barman Ishita,Strop Pavel,Chin Sherman Michael,Pham Amber,Bolton Gary,McDonough Dan,Lindquist Kevin,Pons Jaume,Rajpal Arvind

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

http://www.tandfonline.com/doi/pdf/10.1080/19420862.2015.1008353

Reference40 articles.

1. FcRn: the neonatal Fc receptor comes of age

2. Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics

3. Engineering Human IgG1 Affinity to Human Neonatal Fc Receptor: Impact of Affinity Improvement on Pharmacokinetics in Primates

4. Crystal structure of the complex of rat neonatal Fc receptor with Fc

5. The stoichiometry and affinity of the interaction of murine Fc fragments with the MHC class I-related receptor, FcRn

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