Expression vector-derived heterogeneity in a therapeutic IgG4 monoclonal antibody
Author:
Affiliation:
1. Biologics Analytical Operations, Gilead Sciences, Oceanside, CA, USA
Funder
Gilead Sciences
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2018.1540254
Reference46 articles.
1. Identification of multiple sources of charge heterogeneity in a recombinant antibody
2. Heterogeneity of Monoclonal Antibodies
3. Large-Scale Identification and Quantification of Covalent Modifications in Therapeutic Proteins
4. Structure-dependent nonenzymatic deamidation of glutaminyl and asparaginyl pentapeptides
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