High-throughput screening of antibody variants for chemical stability: identification of deamidation-resistant mutants-Reference-Cited by-同舟云学术

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High-throughput screening of antibody variants for chemical stability: identification of deamidation-resistant mutants

Published:2018-08-21 Issue: Volume: Page:1-11
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

DiCara Danielle M.¹,Andersen Nisana²,Chan Ruby³,Ernst James A.³⁴,Ayalon Gai⁴,Lazar Greg A.¹,Agard Nicholas J.¹,Hilderbrand Amy³,Hötzel Isidro¹

Affiliation:

1. Department of Antibody Engineering, Genentech Inc., South San Francisco, CA, USA

2. Protein Analytical Chemistry, Genentech Inc., South San Francisco, CA, USA

3. Department of Protein Chemistry, Genentech Inc., South San Francisco, CA, USA

4. Department of Neuroscience, Genentech Inc., South San Francisco, CA, USA

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2018.1504726

Reference39 articles.

1. Considerations in Manufacturing Process Development for Antibody-Based Therapeutics

2. Heterogeneity of Monoclonal Antibodies

3. Stability of Protein Pharmaceuticals: An Update

4. Formulation and manufacturability of biologics

5. Antibody Structure, Instability, and Formulation

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Early determination of potential critical quality attributes of therapeutic antibodies in developability studies through surface plasmon resonance-based relative binding activity assessment;mAbs;2024-07-02

2. Stability of Protein Pharmaceuticals: Recent Advances;Pharmaceutical Research;2024-06-27

3. Predicting deamidation and isomerization sites in therapeutic antibodies using structure-based in silico approaches;mAbs;2024-03-28

4. Pertuzumab Charge Variant Analysis and Complementarity-Determining Region Stability Assessment to Deamidation;ANAL CHEM;2023

5. Pertuzumab Charge Variant Analysis and Complementarity-Determining Region Stability Assessment to Deamidation;Analytical Chemistry;2023-02-16

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