Pertuzumab Charge Variant Analysis and Complementarity-Determining Region Stability Assessment to Deamidation-Reference-Cited by-同舟云学术

Pertuzumab Charge Variant Analysis and Complementarity-Determining Region Stability Assessment to Deamidation

Published:2023-02-16 Issue:8 Volume:95 Page:3951-3958
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Spanov Baubek¹,Olaleye Oladapo¹,Mesurado Tomés²,Govorukhina Natalia¹,Jungbauer Alois²^ORCID,van de Merbel Nico C.¹³,Lingg Nico²^ORCID,Bischoff Rainer¹^ORCID

Affiliation:

1. Department of Analytical Biochemistry, Groningen Research Institute of Pharmacy, University of Groningen, A Deusinglaan 1, 9713 AV Groningen, The Netherlands

2. Department of Biotechnology, Institute of Bioprocess Science and Engineering, University of Natural Resources and Life Sciences, Vienna, Muthgasse 18, Vienna 1190, Austria

3. Bioanalytical Laboratory, ICON, Amerikaweg 18, 9407 TK Assen, The Netherlands

Funder

H2020 Marie Sklodowska-Curie Actions

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.2c03275

Reference51 articles.

1. Pertuzumab for the Treatment of Breast Cancer

2. Pertuzumab in Combination with Trastuzumab and Chemotherapy in the Treatment of HER2-Positive Metastatic Breast Cancer: Safety, Efficacy, and Progression Free Survival