1. Osaka Medical Centre for Cancer and Cardiovascular Diseases, Osaka, Japan;
2. International University of Health and Welfare, Otawara, Japan;
3. Hirosaki University, Hirosaki, Japan;
4. University of Occupational and Environmental Health, Kitakyushu, Japan;
5. Osaka National Hospital, Osaka, Japan;
6. Covance Market Access, London, UK;
7. Bayer Yakuhin, Ltd., Tokyo, Japan;
8. Bayer Pharma AG, Berlin, Germany